Research Article

Candidate Selection for Implantation: Noninvasive Predictors of Seizure Onset Zone Focality and Surgical Outcome in People with Drug-Resistant Epilepsy Evaluated by Intracranial Video-EEG Monitoring—A Retrospective Cohort Study

Table 3

Cases with generalised IEDs description.

No.Epilepsy duration (years)Age at evaluation (years)GenderMRI lesion typeSVEM-generalised IEDsSeizuresLocalisation hypothesisSOZ focalitySurgical outcome
SSWPSPSWPFASVEM onsetMain semiology

12225MFCD type II++ (2.5 Hz)+-+NLTonicPLE or OLESublobarLost after Sx
21037FGliosis----+NLTonicFLELobarEngel class IV
33237MSulcation anomaly+-+-+NLClonicPLE or OLESublobarEngel class IV
41213MFCD type I-+ (2.5 Hz)++ (2.5 Hz)+NLTonicFLELobarEngel class IV
51418MFCD type II+----FocalTonicFLELobarEngel class I-A
62626FFCD type II++ (2 Hz)+-+NLTonicFLELobarEngel class IV
72626FNonspecific changes++ (2.5 Hz)--+FocalAutomotorFLEMultilobarEngel class III
81123MMild asymmetry++ (2 Hz)+-+NLTonicFLEMultilobarEngel class IV
93345MMild asymmetry+-+-+NLTonicFLELobarLost after Sx
103339MNonspecific changes++ (2.5 Hz)++ (2.5 Hz)+NLTonicFLEBilateralEngel class III
11311MEncephalocele-+ (3.5 Hz)-+ (3.5 Hz)-FocalAutomotorTLEMultilobarEngel class I-B
122830MFCD type II--++ (2.5 Hz)-NLTonic and clonicTLEBilateralEngel class III
134145FGray-white matter blurring----+NLTonicFLEBilateralNo Sx (nonfocal SOZ)
143034FSulcation asymmetry+----NLTonic and clonicFLELobarEngel class II
151525MNPH (NF1)--+-+NLTonic and clonicTLE and ETEBilateralNo Sx (nonfocal SOZ)
16416MSulcation anomaly++ (2.5 Hz)+-+MultifocalAutomotorTLEMultilobarNo Sx (nonfocal SOZ)
171120FPorencephalic cyst++ (5 Hz)---NLAutomotorTLELobarNo Sx (Thermo)
181039MGliosis-+ (5 Hz)---FocalAutomotorTLESublobarNo Sx (Thermo)

Abbreviations: ETE: extratemporal epilepsy; F: female; FCD: focal cortical dysplasia; FLE: frontal lobe epilepsy; Hz: hertz; IEDs: interictal epileptiform discharges; IVEM: intracranial video-EEG monitoring; M: male; MRI: magnetic resonance imaging; NF1: neurofibromatosis type 1; NL: nonlocalising; No.: number; NPH: nodular periventricular heterotopia; OLE: occipital lobe epilepsy; PFA: paroxysmal fast activity; PLE: parietal lobe epilepsy; PS: polyspikes; PSW: polyspike-and-wave; S: spikes; SOZ: seizure onset zone; SVEM: scalp video-EEG monitoring; SW: spike-and-wave; Sx: surgery; Thermo: stereoelectroencephalography-guided radiofrequency thermocoagulation; TLE: temporal lobe epilepsy.