Agreement between Parkinson Disease Home Diary and Observer Assessments before and after Structured Patient Training

Figure 2

Proportion and temporal agreement of motor states assessed by observer diaries and patients Parkinson’s disease (PD) home diaries before and after diary training. (a) Proportion of “off,” “on without dyskinesia,” and “on with dyskinesia” as assessed by the observer and patient diaries before and after diary training. “Before training” is the participants’ ratings before structured training about motor fluctuations, and “after training” is the same patients’ choices after training (). McNemar-Bowker tests revealed no significant results with  = .495 for baseline and  = .236 for after training data. (b) Temporal agreement rate for “off,” “on without dyskinesia,” and “on with dyskinesia” with the observer ratings as the reference for comparison before and after diary training. Wilcoxon signed rank test tests revealed no significant results when comparing the overall agreement between HD and the observer of HD before and after training assessments (). Agreement was 66% for observed “off” before training and 64% after training (), 74% for observed “on without dyskinesias” before training and 72% after training (), and 58% for observed “on with dyskinesias” before training and 80% after training (). As a comparative group, data from participants of the initial Swedish VALIDATE-PD study cohort, which were not recruited into the study extension, are provided ( values are from McNemar tests). (c) Participants’ choices on the PD home diary in each respective observed motor state before and after diary training. Number of observations in each observed motor state including all patients () in the initial study: “off:” ; “on without dyskinesias:” ; and “on with dyskinesias:” . Numbers of observations in each observed motor state before training (before training): “off:” ; “on without dyskinesias:” ; and “on with dyskinesias:” . Number of observations in each observed motor state after training: “off:” ; “on without dyskinesias:” ; and “on with dyskinesias:” . Note that rounding errors might lead to total percentages above 100%.

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