Joint Association of Low Nadir Serum Sodium and Potassium with Worse Outcomes after Ischemic Stroke
Table 1
Baseline characteristics of the study population, stratified by the nadir NaK scale.
Characteristics
Total
value
Age, years
0.373
Sex (male)
1,754 (60.2%)
517 (62.2%)
838 (62.3%)
399 (54.1%)
<0.001
Medical history, (%)
Hypertension
1,443 (49.4%)
384 (46.2%)
682 (50.6%)
377 (50.9%)
0.083
Diabetes mellitus
523 (17.9%)
128 (15.4%)
257 (19.1%)
138 (18.6%)
0.078
HD history
202 (6.9%)
50 (6.0%)
97 (7.2%)
55 (7.4%)
0.465
Hyperlipidemia
1029 (41%)
296 (41%)
473 (41%)
260 (41%)
0.975
Smoking
936 (32.1%)
292 (35.1%)
435 (32.3%)
209 (28.2%)
0.014
Alcohol
646 (22.1%)
207 (24.9%)
297 (22.0%)
142 (19.2%)
0.025
Clinical status
NIHSS
4 (2-10)
3 (1-6)
4 (2-10)
7 (3-12)
<0.001
GCS
15 (13-15)
15 (14-15)
15 (13-15)
(12–15)
<0.001
SBP (mmHg)
0.019
DBP (mmHg)
0.161
Albumin (g/L)
<0.001
INR (second)
0.001
Blood glucose (mmol/L)
0.001
Urea nitrogen (mmol/L)
5.66 (4.50-7.09)
5.65 (4.57-7.02)
5.74 (4.53-7.21)
5.47 (4.30-6.90)
0.788
Creatinine (μmol/L)
78.0 (66.0-93.2)
79.5 (66.0-93.0)
78.0 (67.0, 94.0)
75.9 (64.0-92.0)
0.265
Triglyceride (mmol/L)
1.29 (0.94-1.86)
1.33 (0.97, 1.87)
1.27 (0.93-1.86)
1.31 (0.95-1.83)
0.404
Electrolyte
s-sodium level baseline
<0.001
s-potassium level baseline
<0.001
s-sodium level
<0.001
s-potassium level
<0.001
Therapy in hospital
Mannitol (mL)
2250 (1250-3750)
1750 (750-3000)
2250 (1250-3500)
2875 (1500-4875)
<0.001
Potassium intake total (g)
9.83 (4.68-15.86)
6.86 (2.81-14.04)
9.62 (4.68-15.44)
9.83 (5.62-17.63)
<0.001
Saline total (mL)
4850 (3000-8200)
4100 (2430-6275)
4900 (3000-8300)
6250 (3500-10200)
<0.001
Complication
Respiratory infection
628 (21.5%)
98 (11.8%)
299 (22.2%)
231 (31.2%)
<0.001
Urinary tract infection
88 (3.0%)
8 (1.0%)
45 (3.3%)
35 (4.7%)
<0.001
Descriptive statistics were calculated using or median (IQR) for continuous variables and frequencies for categorical variables. Abbreviations: HD: heart disease; NIHSS: National Institutes of Health Stroke Scale; GCS: Glasgow Coma Scale; SBP: systolic blood pressure; DBP: diastolic blood pressure; HCT: hematocrit; INR: international normalized ratio; SD: standard deviation; IQR: interquartile range; s-sodium: serum sodium; s-potassium: serum potassium.
