Seizures as Initial Presentation and Enduring Predisposition to Seizures in Autoimmune Encephalitis

Table 2

The characteristics of initial seizures in antibody-positive and antibody-negative AE patients.

Variables	Antibody-positive AE (90, 60.8%)	Antibody-negative AE (58, 38.9%)	value
Seizure type at onset
Generalized, (%)	11 (12.2%)	15 (25.9%)	0.033
Focal motor, (%)	28 (31.1%)	21 (36.2%)	0.520
Focal nonmotor, (%)	6 (6.7%)	8 (13.8%)	0.148
Focal to bilateral, (%)	70 (77.8%)	30 (51.7%)	0.001
Multiple seizure type, (%)	25 (27.8%)	15 (25.9%)	0.798
FBDS, (%)	3 (3.3%)	0	0.160
Seizure frequency at onset
Daily, (%)	45 (50.0%)	34 (58.6%)	0.305
Weekly, (%)	20 (22.2%)	10 (17.2%)	0.462
Monthly, (%)	25 (27.8%)	14 (24.1%)	0.624
Drug resistance to ASMs at onset, (%)	28 (31.1%)	15 (25.9%)	0.492
The number of received ASMs, median [IQR]	2 [1-3]	2 [1-3]	0.411

Abbreviations: FBDS: faciobrachial dystonic seizures; ASMs: antiseizure medications.