Spectral Domain and Angiography Optical Coherence Tomography in Parkinson’s Disease: Structural And Vascular Changes in the Retina Correlate with Disease Severity and Progression

Table 3

Correlations between motor and non-motor symptoms and ophthalmological data.

	VD-SCP^^	VD-DCP^^	FAZ^^^	CC^^	RCP^^	GCC^§	th-RNFL^§	SFCT^§
Age	-0.617/0.001^°	-0.483/0.017	-0.210/0.324	-0.249/0.240	-0.397/0.055	-0-370/0.069	-0.138/0.519	-0.364/0.080
Age at onset	-0.539/0.007	-0.383/0.060	-0.149/0.487	-0.195/0.361	-0.254/0.231	-0.254/0.232	-0.060/0.782	-0.309/0.142
UPDRS-III	-0.349/0.095	-0.428/0.037	-0.373/0.073	-0.356/0.088	-0.108/0.616	-0.108/0.616	-0.089/0.679	-0.071/0.741
UPDRS-IV	-0.572/0.180	-0.153/0.744	-0.420/0.348	-0.552/0.199	-0.416/0.353	-0.088/0.851	-0.685/0.089	-0.776/0.040
HY	-0.352/0.092	-0.152/0.477	-0.622/0.001	-0.133/0.534	-0.094/0.662	-0.113/0.597	-0.550/0.005	-0.035/0.872
SCOPA-AUT	-0.065/0.762	-0.406/0.049	-0.182/0.394	-0.230/0.279	-0.293/0.164	-0.385/0.063	-0.025/0.908	-0.071/0.743
HAM-A	-0.275/0.254	-0.315/0.288	-0.392/0.097	-0.193/0.429	-0.060/0.806	-0.292/0.225	-0.597/0.007	-0.023/0.925
ESS	-0.188/0.380	-0.353/0.090	-0.407/0.048	-0.193/0.367	0.055/0.798	0.277/0.224	-0.090/0.677	-0.025/0.908
PSF-16	-0.451/0.027	-0.700/<0.001	-0.175/0.413	-0.229/0.282	-0.216/0.310	0.149/0.486	-0.416/0.043	-0.090/0.675

VD: vascular density; SCP: superficial capillary plexus: DCP: deep capillary plexus; FAZ: foveal avascular zone; CC: choriocapillaris; RCP: radial peripapillary capillary; GCC: ganglion cell complex; th-RNFL: thickness of retinal nerve fiber layer; SFCT: subfoveal choroidal thickness; UPDRS-III: Unified Parkinson’s Disease Rating Scale section III; UPDRS-IV: Unified Parkinson’s Disease Rating Scale section IV; HY: Hoehn and Yahr scale; SCOPA-AUT: Scales for Outcomes in Parkinson’s Disease-Autonomic Dysfunction; HAM-A: Hamilton Anxiety Scale; ESS: Epworth Sleepiness Scale; PSF-16: Parkinson’s Disease Fatigue Scale-16. ^{^}%; ^{^^}mm; ^§μm; Pearson’s coefficient; ^° value. Significant values are in bold.