Cognitive Impairment and Fatigue in Intensive Care Patients Three Months after the Acute Phase of COVID-19 Infection: Follow-Up with Focus on Differences between the First and Later Waves of the Pandemic
Table 3
Cognitive functioning, fatigue, depression, anxiety, sleep disorder, and vitality in comparison to time periods.
Total
Wave 1
Wave 2+
value
MoCA total score,
Mean (SD) Median (range)
26.2 (3.1) 27 (18-31)
25.9 (3.3) 26 (20-30)
26.5 (3.0) 27 (18-31)
0.550
points
(%)
18 (30%)
10 (38%)
7 (23%)
0.192
General fatigue (MFI-20)
Mean (SD) Median (range)
14.1 (4.2) 15 (2-20) ()
13.1 (4.2) 13.5 (5-20) ()
15.0 (4.0) 15.5 (2-20) ()
0.062
Physical fatigue (MFI-20)
Mean (SD) Median (range)
14.9 (3.8) 15 (6-20) ()
14.0 (3.9) 15 (6-20) ()
15.6 (3.1) 16 (9-20) ()
0.107
Reduced activity (MFI-20)
Mean (SD) Median (range)
13.2 (4.3) 13 (5-20) ()
12.2 (4.3) 12 (5-20) ()
13.9 (4.2) 14 (5-20) ()
0.105
Reduced motivation (MFI-20)
Mean (SD) Median (range)
9.3 (3.9) 8 (4-19) ()
9.2 (3.9) 9 (4-19) ()
9.3 (4.0) 8 (4-19) ()
0.949
Mental fatigue (MFI-20)
Mean (SD) Median (range)
10.2 (4.0) 10 (4-20) ()
9.8 (4.0) 10 (4-20) ()
10.6 (4.0) 10.5 (4-20) ()
0.349
Depression (HADS)
Mean (SD) Median (range)
4.2 (4.2) 3 (0-18) ()
4.0 (4.6) 2 (0-20) ()
4.4 (4.0) 3 (0-18) ()
0.398
Anxiety (HADS)
Mean (SD) Median (range)
4.2 (4.7) 3 (0-17) ()
4.9 (5.4) 2 (0-17) ()
4.6 (4.1) 4 (0-13) ()
0.859
Sleep disorder (ISI)
Mean (SD) Median (range)
10.1 (7.2) 8 (0-28) ()
10.4 (7.1) 8 (0-24) ()
9.9 (7.3) 8 (0-27) ()
0.638
General health (RAND-36)
Mean (SD) Median (range)
47.5 (19.2) 45 (5-80) ()
44.1 (22.4) 45 (5-80) ()
50.5 (17.0) 50 (15-80) ()
0.266
Vitality (RAND-36)
Mean (SD) Median (range)
47.9 (22.4) 50 (5-100) ()
51.0 (25.3) 55 (5-100) ()
45.4 (19.2) 40 (5-85) ()
0.312
Values are displayed as mean, standard deviation (SD), median, and range. values for differences between waves 1 and 2+ are presented. Mann–Whitney -test was used for discrepancy analysis. Confidence interval was set at 95% for all variables.
