Dietary Fish Meal Level and a Package of Choline, β-Glucan, and Nucleotides Modulate Gut Function, Microbiota, and Health in Atlantic Salmon (Salmo salar, L.)
Table 10
Enrichment of functional categories of Gene Ontology among genes that showed an association between expression profiles and FM level (diets with supplements were not included in analysis).
Functional group
DEG1
Genes2
value3
Upregulated
Glutathione metabolism
13
78
0.0
Xenobiotic metabolic process
17
113
0.0
Glycine serine and threonine metabolism
7
67
0.001
Lysine degradation
6
62
0.004
Valine leucine and isoleucine degradation
7
73
0.002
Tryptophan metabolism
12
69
0.0
Glycerolipid metabolism
6
76
0.017
Mitochondrion
67
1485
0.0
Retinol metabolism
12
83
0.0
Steroid metabolic process
8
67
0.0
Heme binding
11
212
0.040
Iron ion binding
16
217
0.0
Metallocarboxypeptidase activity
7
27
0.0
Lysosome
26
363
0.0
Chemokine activity
6
57
0.002
Lymphocyte chemotaxis
6
38
0.0
Epithelial cell differentiation
9
94
0.0
Downregulated
Chromatin binding
15
578
0.029
DNA replication
9
196
0.001
G1/S transition of mitotic cell cycle
5
126
0.048
Mismatch repair
5
49
0.0
Cadherin binding
15
533
0.012
ECM-receptor interaction
10
161
0.0
Extracellular matrix structural constituent
8
222
0.016
Focal adhesion
10
345
0.040
Collagen
9
183
0.0
1Number of differentially expressed genes per term. 2Number of genes on the microarray platform. 3Yates’ corrected chi-test.
