Orthopaedic Aspects of Marfan Syndrome: The Experience of a Referral Center for Diagnosis of Rare Diseases

<div>A twenty-year-old female affected by Marfan syndrome with an associated wrist and thumb sign. The “wrist sign” is positive when the thumb overlaps the fifth finger when grasping the contralateral wrist. The “thumb sign” is positive when the thumb extends well beyond the ulnar border of the hand when overlapped by the fingers.</div>

Advances in Orthopedics

fig1

Figure 1

Figure 1: Orthopaedic Aspects of Marfan Syndrome: The Experience of a Referral Center for Diagnosis of Rare Diseases 