Platelet-Rich Plasma and Adipose-Derived Mesenchymal Stem Cells in Association with Arthroscopic Microfracture of Knee Articular Cartilage Defects: A Pilot Randomized Controlled Trial

Table 2

ICRS (International Cartilage Research Society) Visual Histological Assessment Scale.

Feature	Points
Surface; Smooth/continuous; Discontinuities/irregularities	3; 0
Matrix; Hyalin mixture: hyaline/fibrocartilage; Fibrocartilage Fibrous tissue	3; 2; 1; 0
Cell distribution; Columnar; Mixed/columnar-clusters; Clusters; Individual cells/disorganized	3; 2; 1; 0
Cell population viability; Predominantly viable; Partially viable; <10% viable	3; 1; 0
Subchondral bone; Normal; Increased remodelling; Bone necrosis/granulation tissue; Detached/fracture/callus at base	3; 2; 1; 0
Cartilage mineralization (calcified cartilage); Normal; Abnormal/inappropriate location	3; 0