Research Article

Evaluation of Absolute Neutrophil Count in the Perioperative Setting of Sarcoma Resection

Table 5

Univariate and multivariate analyses for overall survival.

Univariate analysis valueMultivariate analysis value

Tumor grade (low vs intermediate/high)HR 4.798 (95% CI 1.128–20.145)0.019HR 2.183 (95% CI 0.450–10.593)0.333
Metastasis at time of surgeryHR 3.397 (95% CI 1.366–8.449)0.005HR 2.845 (95% CI 0.753–8.199)0.135
Pathologic fractureHR 2.700 (95% CI 1.130–6.452)0.025HR 2.990 (95% CI 1.099–8.135)0.032
Perioperative chemotherapyHR 1.619 (95% CI 0.711–3.684)0.251
Perioperative radiotherapyHR 2.692 (95% CI 1.259–5.756)0.011HR 2.257 (95% CI 0.928–5.845)0.073
Preoperative ANC (below vs above 1000)HR 0.689 (95% CI 0.093–5.115)0.714
Preoperative ALC (below vs above 1000)HR 0.753 (95% CI 0.284–2.001)0.570
Operative timeHR 1.003 (95% CI 1.00–1.005)0.024HR 1.002 (95% CI 0.999–1.006)0.179
Length of stayHR 1.069 (95% CI 1.013–1.128)0.024HR 0.954 (95% CI 0.804–1.131)0.587
Postoperative complicationsHR 0.758 (95% CI 0.321–1.794)0.529
Surgical complication within 30 daysHR 2.449 (95% CI 0.575–10.426)0.225
Return to OR in 30 daysHR 0.049 (95% CI 0.000–2037084.398)0.736
ReoperationHR 0.379 (95% CI 0.131–1.094)0.073

ANC, absolute neutrophil count; ALC, absolute lymphocyte count; OR, operating room; statistically significant values are bolded.