Niosome: A Promising Nanocarrier for Natural Drug Delivery through Blood-Brain Barrier

Table 1

Recent studies in drug delivery using niosomes

Application	Surfactant	Method	Drug	Route administration	Reference
Pulmonary delivery	Tween 60	Lipid layer hydration	Ciprofloxacin	Inhaler	[71]
	Span 60	Lipid layer hydration	Clarithromycin	Inhaler	[72]
	Span 60	Sonication	Rifampicin	Intratracheal	[73]
Protein delivery	Brij 92	Lipid layer hydration	Insulin	Oral	[74]
	Span 60	Lipid layer hydration	Insulin	Oral	[75]
	Span 40	Lipid layer hydration	N-acetyl glucosamine	Topical	[76]
	Span 60	Lipid layer hydration	Bovine serum albumin	Oral	[77]
Cancer chemotherapy	Span 60	Lipid layer hydration	Cisplatin		[78]
	Span 60	Lipid layer hydration	5-Flourouracil	Topical	[79]
	Span 80	Sonication	Curcumin		[79]
	Bola surfactant	Lipid layer hydration	5-Fluorouracil	Intravenous	[80]
	Span 60	Lipid layer hydration	5-Fluorouracil	Topical	[81]
Carrier for hemoglobin	Span 60	Lipid layer hydration	Hemoglobin	Intravenous	[82]
Treatment of HIV-AIDS	Span 60	Lipid layer hydration	Lamivudine		[83]
	Span 60	Ether injection	Stavudine		[84]
	Span 60	Lipid layer hydration	Stavudine		[31]
	Span 80	Eether injection	Zidovudine		[85]
Vaccine and antigen delivery	Span 60	Lipid layer hydration	Tetanus toxoid		[86]
	Span 20	Lipid layer hydration	Newcastle disease vaccine	Parenteral	[87]
	Span 60	Lipid layer hydration	Ovalbumin		[88]
	Span 60/span 85	Reversed- phase evaporation	Bovine serum albumin	Topical vaccine	[89]