Attenuation of Age-Related Hepatic Steatosis by Dunaliella salina Microalgae in Senescence Rats through the Regulation of Redox Status, Inflammatory Indices, and Apoptotic Biomarkers

Figure 4

Effect of D. salina on hepatic content of caspase-3 in albino rats with age-related hepatic steatosis. Age-related hepatic steatosis was induced in rats by injections of D-galactose (200 mg/kg I.P) for eight weeks. Rats injected with oral D-galactose for two weeks were treated with BDS (450 mg/kg), PDS (30 mg/kg), CDS (30 mg/kg), or ZH (250 μg/kg). Twenty-four hours later, the last dose of the treatment, rats were sacrificed and liver tissues were homogenized. Tissue homogenate were used for caspase assessment. Data are expressed as mean ± SEM from the normal value. Statistical analysis was performed by one-way analysis of variance (ANOVA) followed by the Tukey–Kramer test for multiple comparisons. Significantly different from the normal control group at . ^@Significantly different from D-galactose control at .