Research Article
Attenuation of Age-Related Hepatic Steatosis by Dunaliella salina Microalgae in Senescence Rats through the Regulation of Redox Status, Inflammatory Indices, and Apoptotic Biomarkers
Table 3
Effect of D. salina on hepatic redox status biomarkers in albino rats with age-related hepatic steatosis.
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Age-related hepatic steatosis was induced in rats by injections of D-galactose (200 mg/kg I.P) for eight weeks. Rats injected with oral D-galactose for two weeks were treated with BDS (450 mg/kg), PDS (30 mg/kg), CDS (30 mg/kg), or ZH (250 μg/kg). Twenty-four hours later, the last dose of the treatment, rats were sacrificed, liver tissue was isolated and homogenized, and the tissue homogenate was used for hepatic catalase, GST, and MPO measurements. Data are expressed as mean ± SEM from the normal value. Statistical analysis was performed by one-way analysis of variance (ANOVA) followed by the Tukey–Kramer test for multiple comparisons. Significantly different from the normal control group at P ≤ 0.05. @Significantly different from D-galactose control at P ≤ 0.05. |