Hypoglycemic Effect of a Combined Andrographis paniculata and Caesalpinia sappan Extract in Streptozocin-Induced Diabetic Rats

Figure 3

(a) Histological interpretation of the adipose tissue in rats (H&E, 40x). (A) Section from the NC group showing large adipocytes of normal rats; (B) section from diabetic rats of the DM group showing large adipocytes cells; (C) section from the MET group (diabetic rats + metformin) showing large adipocytes; (D) section from APE groups (diabetic rats + APE 100 mg) showing mixed adipocytes large and small, mostly massive; (E) CSE group (diabetic rats + CSE 100 mg) showing mixed adipocytes with large and small cells, mostly small sizes; (F) APCSE100 and (G) APCSE200 offer diverse cell sizes, but most are the smaller size of adipocytes. (b) Adipocyte cell count. Adipocyte cell count in the CSE, APCSE100, and APCSE200 groups was significantly different compared to the DM group. Results presented are mean ± SEM; significantly different from DM and significantly different from normal .

(a)

(b)