Ascorbic Acid Significantly Decreases Creatine Kinase Plasma Levels in an Animal Model of Statin/Fibrate-Induced Myopathy

Figure 4

Aldolase levels of rats were compared between control and treated groups. ATV, atorvastatin (80 mg/kg/day for 10 days); GMF, gemfibrozil (1000 mg/kg/day for 10 days). Swimming was done in days 8, 9, and 10. The levels of each bar are mean, and the error bar is SEM (n = 6 in each group). ^∗ value <0.01 compared with the control without swim group. value <0.05 in comparison with the ATV/GMF without swim group. ^# value <0.05 in comparison with the control without swim group. One-way ANOVA followed by Tukey’ post hoc test.