Review Article
Phylogeny, Phytomedicines, Phytochemistry, Pharmacological Properties, and Toxicity of Croton gratissimus Burch (Euphorbiaceae)
Table 6
Activities of various leaf extracts of
Croton gratissimus and standard (doxorubicin hydrochloride) on noncancerous and cancerous cell lines [
16].
| | Extracts | LC50 (μg/mL) | IC50 (μg/mL) and selectivity index = LC50/IC50 | | Vero | A549 | SI | CaCO-2 | SI | HeLa | SI | MCF-7 | SI |
| | Acetone | 462.88 | 97.46 | 4.75 | 74.05 | 6.25 | 78.21 | 5.91 | 83.74 | 5.52 | | Ethanol | 152.30 | 79.60 | 1.91 | 48.46 | 3.14 | 73.78 | 2.06 | 39.75 | 3.83 | | Water | 533.33 | >200 | <2.66 | >200 | <2.66 | >200 | <2.66 | >200 | <2.66 | | Doxorubicin | 1.90 | 1.30 | 1.46 | 1.08 | 1.75 | 2.17 | 0.87 | 1.11 | 1.71 |
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