In Vitro and In Vivo Antiproliferative Actions of Solanum gilo Raddi (Solanaceae) Fruit Extract on Breast Tissues

Figure 3

Effects of S. gilo hydroethanolic extract on microphotographs H&E 100× and 400× of mammary glands after 16 weeks of treatment. NOR = Normal control treated with distilled water; E2V = E2V-control treated with distilled water; SG + E2V = Animals treated with the S. gilo hydroethanolic extract at the doses of 125, 250, and 500 mg/kg BW. TAMOX + E2V = Animals treated with tamoxifen (3.3 mg/kg BW); all groups except the normal group (NOR) received chronic administration of E2V at the dose of 1 mg/kg BW. La = lumen of alveoli; At = adipose tissue; Se = eosinophil secretion, L = lobular; HLU = hyperplastic lobular unit.