Solubility Enhancement of a Poorly Water-Soluble Drug Using Hydrotropy and Mixed Hydrotropy-Based Solid Dispersion Techniques

Figure 7

A comparative X-ray diffractogram of pure rosuvastatin ROS, hydrotropic agents (urea, sodium benzoate, and sodium salicylate), rosuvastatin solid dispersions (SDRE and SDFD), and rosuvastatin physical mixture (PM).