Solubility Enhancement of a Poorly Water-Soluble Drug Using Hydrotropy and Mixed Hydrotropy-Based Solid Dispersion Techniques

Table 6

Determination of the percentage drug content of rosuvastatin solid dispersions SDRE, SDFD, and physical mixture.

NO SI	Solid dispersion	% drug content
1	SDRE	102.339 ± 1.378
2	SDFD	104.963 ± 0.149
3	PM	103.154 ± 0.605

SDRE, rosuvastatin solid dispersion by the rotary evaporator; SDFD, rosuvastatin solid dispersion by the freeze dryer; PM, rosuvastatin physical mixture. The data are presented as the mean ± SD (n = 3).