Antiplasmodial, Antitrypanosomal, and Cytotoxic Effects of Anthonotha macrophylla, Annickia polycarpa, Tieghemella heckelii, and Antrocaryon micraster Extracts

Table 3

IC₅₀ of the extracts against P. falciparum, T. brucei, and RAW 264.7 cell line inhibitions.

Extracts	P. falciparum	T. brucei	Cytotoxicity
	IC50 (µg/mL)
AML	5.0 ± 0.08	13.6 ± 0.21	109.4 ± 0.12
APLE	110.1 ± 0.12	53.0 ± 0.05	76.5 ± 0.22
THBE	28.8 ± 0.16	11.0 ± 0.09	112.0 ± 0.32
AMSBE	24.5 ± 0.21	19.9 ± 0.15	98.5 ± 0.24
DA	—	1.1 ± 1.13	74.1 ± 0.31
CHL	0.146 ± 0.05	—	6.88 ± 0.32