Advances in Pharmacological and Pharmaceutical Sciences

Research Article

Phytochemical Analysis, Antifungal, and Antioxidant Properties of Two Herbs (Tristemma mauritianum and Crassocephalum bougheyanum) and One Tree (Lavigeria macrocarpa) Species

Table 6

Antifungal activity (MIC and MFC in μg/mL) of plant extracts and reference antifungal drugs against Candida spp.


Yeast species	T. mauritianum (aerial parts)		L. macrocarpa (leaves)		L. macrocarpa (roots)		C. bougheyanum (aerial parts)		Fluconazole		Ketoconazole
Yeast species	MIC	MFC	MIC	MFC	MIC	MFC	MIC	MFC	MIC	MFC	MIC	MFC

C. dubliniensis 5 : I52	256	1024	—	—	512	—	2048	—	256	—	16	128
C. dubliniensis 1 : I59	64	512	—	—	2048	—	512	—	—	—	256	—
C. dubliniensis 3 : I81	256	—	1024	—	1024	—	1024	—	256	—	256	—
C. albicans ATCC 10231	64	256	256	—	256	512	256	—	1	1	2	2
C. albicans 7Ca	128	1024	1024	—	512	2048	1024	—	256	—	128	256
C. albicans 11Ca	256	—	—	—	—	—	1024	—	—	—	16	64
C. albicans 18Ca	64	1024	512	—	256	2048	256	—	256	—	64	64
C. albicans Cppc BACT 017	256	—	2048	—	1024	—	1024	—	128	256	32	64
C. glabrata 11 : I81	128	—	2048	—	1024	—	1024		—	—	64	256
C. glabrata 10 : I39	128	—	1024	—	512	—	512	—	128		16	64
C. tropicalis Cpc BACT 018	64	2048	512	—	512	—	—	—	256	—	128	128

—: >2048 µg/mL; MIC: minimum inhibitory concentration; MFC: minimum fungicidal concentration. Values in bold indicate the significant activity (MIC<100 µg/mL).