Combination of Chemically-Characterized Essential Oils from Eucalyptus polybractea, Ormenis mixta, and Lavandula burnatii: Optimization of a New Complete Antibacterial Formulation Using Simplex-Centroid Mixture Design

Table 6

FIC indices of the combined antibacterials against the tested bacterial strains.

Bacteria	Samples		MIC % (v/v)		FIC % (v/v)	FIC index	Effect
			Alone	Combination
S. aureus ATCC 29213	1/2	EPEO	0.25	0.125	0.5	0.656	Partial synergy
	1/4	OMEO	0.5	0.0078	0.0156
	1/4	EPEO	0.25	0.0625	0.25	0.281	Synergy
	1/32	OMEO	0.5	0.0156	0.0312
	1/8	EPEO	0.25	0.3125	0.125	0.1874	Synergy
	1/16	OMEO	0.5	0.0312	0.0624
	1/32	EPEO	0.25	0.007813	0.03125	0.156	Synergy
	1/8	OMEO	0.5	0.0625	0.125
	1/64	EPEO	0.25	0.0039	0.0156	0.2656	Synergy
	1/4	OMEO	0.5	0.125	0.25
	1/256	EPEO	0.25	0.00976	0.003907	0.5039	Partial synergy
	1/2	OMEO	0.5	0.25	0.25
	1/2048	EPEO	0.25	0.0001220	0.00048828	0.25	Synergy
	1/4	LBEO	0.25	0.0625	0.25
	1/4096	EPEO	0.25	6.103.10^−5	0.00024412	0.5002	Partial synergy
	1/2	LBEO	0.25	0.125	0.5
	1/4	LBEO	0.25	0.0625	0.25	0.75	Partial synergy
	1/2	OMEO	0.5	0.25	0.5
E. coli ATCC 25922	1/2	EPEO	2	1	0.5	0.625	Partial synergy
	1/8	OMEO	6	0.75	0.125
	1/4	EPEO	2	0.5	0.25	0.5	Synergy
	1/4	OMEO	6	1.5	0.25
	1/4096	EPEO	2	0.00048828	0.00024414	0.50024414	Partial synergy
	1/2	OMEO	6	3	0.5
	1/8	EPEO	2	0.25	0.125	0.625	Partial synergy
	1/2	LBEO	1	0.5	0.5
	1/4	EPEO	2	0.5	0.25	0.25195313	Synergy
	1/512	L.BEO	1	0.00195313	0.00195313
	1/2	EPEO	2	1	0.5	0.50024414	Partial synergy
	1/4096	LBEO	1	0.00024414	0.00024414
	1/2	LBEO	1	0.5	0.5	0.625	Partial synergy
	1/8	OMEO	6	0.75	0.125
	1/2	LBEO	1	0.25	0.25	0.5	Synergy
	1/4	OMEO	6	1.5	0.25
	1/16	LBEO	1	0.0625	0.0625	0.5625	Partial synergy
	1/2	OMEO	6	3	0.5