Research Article
Drug Utilization Evaluation of Erythropoietin at a Referral Teaching Hospital in Iran
Table 2
Comparison of total erythropoietin administration indices with standard instructions in the study population (n = 230).
| Index | Appropriate (%) | Inappropriate (%) | value |
| Dose | 52.6 | 47.4 | 0.2293 | Intervals and frequency of administration | 77.4 | 22.6 | <0.0001 | Route of administration | 100 | 0 | <0.0001 | Indication | 56.1 | 43.9 | 0.1056 | Monitoring of laboratory and clinical parameters before and during treatment | 54.3 | 45.7 | 0.1085 | Proportion of dose adjustment based on response rate | 98.1 | 1.9 | <0.0001 | Attention to the target Hb ≥ 12 to decide whether or not to continue treatment | 93 | 7 | <0.0001 | Attention to absolute and relative contraindications | 98.7 | 1.3 | <0.0001 | Monitoring drug interactions | 98.7 | 1.3 | <0.0001 | Administration of injectable or oral iron supplements during treatment (only in CKD patients) | 29.5 | 70.5 | <0.0001 |
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Hb: hemoglobin, CKD: chronic kidney disease.
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