Drug Utilization Evaluation of Erythropoietin at a Referral Teaching Hospital in Iran

Table 2

Comparison of total erythropoietin administration indices with standard instructions in the study population (n = 230).

Index	Appropriate (%)	Inappropriate (%)	value
Dose	52.6	47.4	0.2293
Intervals and frequency of administration	77.4	22.6	<0.0001
Route of administration	100	0	<0.0001
Indication	56.1	43.9	0.1056
Monitoring of laboratory and clinical parameters before and during treatment	54.3	45.7	0.1085
Proportion of dose adjustment based on response rate	98.1	1.9	<0.0001
Attention to the target Hb ≥ 12 to decide whether or not to continue treatment	93	7	<0.0001
Attention to absolute and relative contraindications	98.7	1.3	<0.0001
Monitoring drug interactions	98.7	1.3	<0.0001
Administration of injectable or oral iron supplements during treatment (only in CKD patients)	29.5	70.5	<0.0001

Hb: hemoglobin, CKD: chronic kidney disease.