Research Article

Development of the RP-HPLC Method for Simultaneous Determination and Quantification of Artemether and Lumefantrine in Fixed-Dose Combination Pharmaceutical Dosage Forms

Table 2

Linearity results for artemether and lumefantrine.

APIConcentration (μg/mL)Mean peak area (mAUs)

Artemether27562.420.9992
550125.70
660150.43
880202.91
1100241.94
1320304.57
1540351.16
1650378.57
1925441.59

Lumefantrine1502385.890.9985
3004820.10
3605721.26
4807787.03
6009461.54
72011774.6
84013336.3
90014236.7
105016270.3