Investigation of Herb-Drug Interactions between Xylopia aethiopica, Its Principal Constituent Xylopic Acid, and Antidepressants

Figure 1

HPLC-UV chromatogram of Xylopia aethiopica extract in methanol using isocratic elution of methanol : water (90 : 10). Detection wavelength = 206 nm (a). HPLC-UV chromatogram of isolated xylopic acid in methanol using isocratic elution of methanol : water (90 : 10). Detection wavelength = 206 nm.  = 3.368 min (b).

(a)

(b)