Research Article

Investigation of Herb-Drug Interactions between Xylopia aethiopica, Its Principal Constituent Xylopic Acid, and Antidepressants

Figure 7

Isobolograms for oral coadministration of xylopic acid with (a) imipramine, (b) fluoxetine, and (c) venlafaxine. The theoretical ED50 for an additive effect and the experimental ED50 values are represented in the graphs.
(a)
(b)
(c)