Synthetic Archaeosome Vaccines Containing Triglycosylarchaeols Can Provide Additive and Long-Lasting Immune Responses That Are Enhanced by Archaetidylserine
Figure 1
Semisynthetic glycoarchaeol structures showing head group details. “A” is the archaeol lipid precursor used for synthesis. gentiobiosyl-A (-Glcp-(1→6)--Glcp-(1→O)-archaeol); Gentiotriosyl-A (-Glcp-(1→6)--Glcp-(1→6)--Glcp-(1→O)-archaeol); mannotriosyl-A (-Manp-(1→2)--Manp-(1→2)--Manp-(1→O)-archaeol); maltotriosyl-A (-Glcp-(1→4)--Glcp-(1→4)--Glcp-(1→O)-archaeol).
