Research Article

The Effect of Malathion Concentration and Exposure Time on Histopathological Changes in the Liver and Gill of Rainbow Trout

Table 2

Grading of histopathological changes observed in liver tissues.

Grade of tissue damageHistopathological changes

1Normal liver
2Hepatocyte necrosis; hepatocyte malformation; melanomacrophage centers
3Hyperemia; sinusoid necrosis; degeneration; hepatocyte malformation
4Bile duct necrosis; aneurysm; cholestasis; inflammatory cell infiltration
5Hyperemia; hepatocyte necrosis; vacuolation; cell atrophy