Research Article
The Effect of Malathion Concentration and Exposure Time on Histopathological Changes in the Liver and Gill of Rainbow Trout
Table 2
Grading of histopathological changes observed in liver tissues.
| Grade of tissue damage | Histopathological changes |
| 1 | Normal liver | 2 | Hepatocyte necrosis; hepatocyte malformation; melanomacrophage centers | 3 | Hyperemia; sinusoid necrosis; degeneration; hepatocyte malformation | 4 | Bile duct necrosis; aneurysm; cholestasis; inflammatory cell infiltration | 5 | Hyperemia; hepatocyte necrosis; vacuolation; cell atrophy |
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