Autologous Blood Transfusion after Local Infiltration Analgesia with Ropivacaine in Total Knee and Hip Arthroplasty

Table 2

Comparison of studies in autotransfusion after LIA with ropivacaine.

Characteristic	Present study	Gill et al. [6]	Breindahl et al. [7]	Parker et al. [5]	Stringer et al. [21]
Number of patients	25 TKA,; 27 THA	10 THA^*	20 TKA,; 10 THA	20 TKA	15 TKA,; 20 THA
Autotransfusion performed	Yes	Yes	No	Yes	No
Ropivacaine dose for LIA (mg)	200	400	200	150	360–400
Drainage blood volume (mL)	93–977	<1250	50–620	300–700	10–905
Drainage blood content of ropivacaine (mg)	<7.2	<6	0.28–12	<2.6	0.53–27
Infusion rate (mg/h)	0.42–12	—	—	0.7–4.7	—
Serum concentration before autotransfusion (μg/mL)	<0.79	—	<1.1	<0.79	<2
Serum concentration after autotransfusion (μg/mL)	<1.0	—	—	<1.5	—
Free ropivacaine concentration after autotransfusion (μg/mL)	<0.038	—	—	—	—
Max. concentration after bolus injection I	1.9	—	1.5	—	—
Max. concentration after bolus injection II	2.6	—	—	—	—

^* Peri-articular multimodal analgesia (PMDI).