Anesthesiology Research and Practice / 2021 / Article / Tab 4 / Research Article
Acute Effects of Ketamine Infusion on Postoperative Mood Scores in Patients Undergoing Dilation and Curettage: A Randomized Double-Blind Controlled Study Table 4 Comparison according to POMS (2/2).
Items Time Ketamine (N = 30) Control (N = 30) Effect of ketamine relative to control RMANOVA P values Mean ± SD Between subjects Between subjects Within subjects Inter-action Depression Depressed Pre 1.8 ± 0.8 1.8 ± 1.1 0.0 ± 0.2 −0.5–0.5 0.002 0.355 <0.001 Post 1.0 ± 0.6 2.4 ± 1.2 −1.5 ± 0.2 −2.0–1.0 Down hearted Pre 1.8 ± 0.5 1.7 ± 1.1 0.1 ± 0.2 −0.4–0.6 0.036 0.141 <0.001 Post 1.4 ± 0.6 2.3 ± 1.0 −0.9 ± 0.2 −1.3–0.5 Miserable Pre 1.8 ± 0.8 1.9 ± 1.1 −0.1 ± 0.2 −0.6–0.4 0.002 0.261 <0.001 Post 1.3 ± 0.9 2.6 ± 1.0 −1.4 ± 0.2 −1.9–0.9 Unhappy Pre 2.8 ± 1.2 3.1 ± 1.1 −0.3 ± 0.3 −0.9–0.3 0.005 <0.001 0.001 Post 1.6 ± 0.8 2.8 ± 1.1 −1.1 ± 0.2 −1.6–0.7 Total depression subscale Pre 8.1 ± 2.3 8.4 ± 2.8 −0.3 ± 0.7 −1.6–1.1 <0.001 0.005 <0.001 Post 5.3 ± 1.9 10.2 ± 3.4 −4.9 ± 0.7 −6.3–3.4 Confusion Confused Pre 1.1 ± 0.9 1.1 ± 1.0 0.0 ± 0.2 −0.4–0.5 0.005 0.430 <0.001 Post 0.5 ± 0.5 1.6 ± 0.7 −1.1 ± 0.2 −1.4–0.8 Mixed up Pre 1.3 ± 0.7 1.2 ± 1.0 0.1 ± 0.2 −0.4–0.5 0.177 0.001 <0.001 Post 1.2 ± 0.8 1.9 ± 0.9 −0.6 ± 0.2 −1.1–0.2 Muddled Pre 1.7 ± 1.2 1.5 ± 0.8 0.2 ± 0.3 −0.3–0.7 0.001 0.119 0.001 Post 0.6 ± 0.7 2.1 ± 1.0 −1.5 ± 0.2 −2.0–1.1 Uncertain Pre 1.3 ± 1.2 1.3 ± 0.9 0.1 ± 0.3 −0.5–0.6 0.001 0.536 <0.001 Post 0.6 ± 0.7 2.2 ± 1.0 −1.6 ± 0.2 −2.0–1.2 Total confusion subscale Pre 5.4 ± 3.1 5.0 ± 2.1 0.4 ± 0.7 −1.0–1.7 <0.001 0.603 <0.001 Post 2.9 ± 1.6 7.7 ± 2.1 −4.9 ± 0.5 −5.8–3.9 Anger Angry Pre 1.0 ± 0.7 1.1 ± 1.0 −0.2 ± 0.2 −0.6–0.3 0.001 0.366 <0.001 Post 0.4 ± 0.5 1.5 ± 0.8 −1.1 ± 0.2 −1.5–0.7 Annoyed Pre 1.7 ± 0.6 1.5 ± 0.7 0.2 ± 0.2 −0.1–0.6 0.752 0.252 0.007 Post 1.5 ± 0.7 1.9 ± 0.9 −0.3 ± 0.2 −0.7–0.1 Bad tempered Pre 2.2 ± 0.8 2.1 ± 1.2 0.1 ± 0.3 −0.5–0.6 0.715 <0.001 0.214 Post 1.5 ± 0.7 1.7 ± 1.2 −0.2 ± 0.2 −0.7–0.3 Bitter Pre 1.9 ± 1.4 1.7 ± 1.3 0.1 ± 0.3 −0.5–0.8 0.552 0.005 0.010 Post 1.2 ± 1.2 1.7 ± 1.3 −0.5 ± 0.3 −1.1–0.1 Total anger subscale Pre 6.7 ± 2.5 6.4 ± 1.9 0.3 ± 0.6 −0.9–1.4 0.095 <0.001 <0.001 Post 4.7 ± 2.0 6.8 ± 2.6 −2.2 ± 0.6 −3.4–1.0 Total POMS Preoperative 28.1 ± 8.0 27.8 ± 9.5 0.3 ± 2.3 −4.3–4.8 <0.001 <0.001 <0.001 Postoperative 11.9 ± 5.4 37.3 ± 13.0 −25.4 ± 2.6 −30.5–20.2
∧ RMANOVA test.
Significant.