Research Article
Hemodynamic Effects of Methamphetamine and General Anesthesia
Table 2
Comparison of clinical outcomes among the three study groups.
| | No meth (n = 159) | Subacute positive (n = 69) | Acute positive (n = 137) | value |
| | Blood pressure at 0 min (SBP/DBP (MAP) mean ± SD) | | | | | | Heart rate at 0 min (mean ± SD) | 85.9 ± 9.4 | 86 ± 12 | 91.2 ± 13.4 | 0.0002 | | Blood pressure between 5 and 60 min (SBP/DBP (MAP) mean ± SD) | | | | | | Mean HR between 5 and 60 min (mean ± SD) | 75.1 ± 12 | 78.3 ± 12.1 | 83.8 ± 15 | <.0001 | | Hemodynamic instability, n (%) | 10 (6.3) | 18 (26.1) | 43 (31.4) | <.0001 | | Hemodynamic instability by MAP criteria only, n | 2 | 0 | 6 | | | Hemodynamic instability by medication criteria only, n | 8 | 17 | 28 | | | Hemodynamic instability by both criteria, n | 0 | 1 | 9 | |
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DBP: diastolic blood pressure. HR: heart rate. MAP: mean arterial blood pressure. SBP: systolic blood pressure. SD: standard deviation.
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