Single Dose Intravenous Paracetamol versus Placebo in Postorthognathic Surgery Pain: A Randomized Clinical Trial
Table 2
Pain scores, morphine consumption, and patients’ satisfaction according to the treatment groups.
Characteristics
Study group (n = 31)
Control group (n = 31)
value
VAS pain scale, mean ± SD
1 hour
1.2 ± 1.4
5.1 ± 2.1
<0.001
4 hour
0.8 ± 1.3
4.2 ± 1.4
<0.001
8 hour
1.3 ± 1.4
3.5 ± 1.1
<0.001
12 hour
1.3 ± 1.4
2.9 ± 1.3
<0.001
16-hour
1.0 ± 1.1
2.3 ± 1.6
<0.001
20-hour
0.7 ± 0.9
2.3 ± 1.4
<0.001
24-hour
0.6 ± 0.9
1.8 ± 1.3
<0.001
Morphine consumption (mcg/kg), mean ± SD
45.1 ± 21.2
136.5 ± 49.9
<0.001
Satisfaction (0–5), mean ± SD
4.7 ± 0.5
4.1 ± 0.7
<0.001
Differences between treatment groups were tested using MANOVA. A significant difference after Bonferroni multiple testing correction is indicated in bold.