Patient Characteristics Associated with HCV Treatment Adherence, Treatment Completion, and Sustained Virologic Response in HIV Coinfected Patients

Table 2

Patient characteristics and HCV treatment completion.

Variable	Treatment complete (𝑁=43)	Treatment discontinued (𝑁=26)	P-value
Demographics
Male gender	93%	96%	0.59
African American	30%	31%	0.96
Mean age (years)	47.2	50.9	0.12
Any college education	58%	58%	0.97
Employed	37%	31%	0.59
In a relationship	24%	19%	0.66
HIV Disease characteristics
Mean CD4 count (cells/mm^3)	507	534	0.65
Mean log10 HIV RNA (copies/ml)	2.29	2.17	0.63
HIV RNA ≤400	79%	77%	0.81
HCV Disease characteristics
HCV genotype 1 or 4	65%	81%	0.17
Mean log10 HCV RNA (copies/ml)	6.08	6.24	0.39
HCV RNA <800,000	45%	38%	0.57
Psychosocial functioning
Depressive disorder	36%	50%	0.26
Any psychiatric disorder	40%	58%	0.15
Any drinking problem	12%	23%	0.21
Any illicit drug use	12%	15%	0.65
Any missed clinic appointments (past 6 months)	35%	23%	0.30
Good HCV treatment adherence^∗1	79%	55%	0.04

^∗𝑃<0.05.
¹Good adherence is defined as 100% adherence.