Clinical Study

Clinical Feature of Men Who Benefit from Dose Escalation of Naftopidil for Lower Urinary Tract Symptoms: A Prospective Study

Table 1

Patients’ demographics and the baseline International Prostate Symptom Score (IPSS).

Total75 mg group50 mg group 𝑃 value
( 𝑛 = 4 6 )( 𝑛 = 3 5 )( 𝑛 = 1 1 )(75 mg versus 50 mg)

Age, mean (years)71.7 ± 9.472.1 ± 9.270.2 ± 10.5.559
Prostate volume, mean (mL)31.7 ± 24.834.6 ± 24.925.0 ± 24.8.403
Residual urine, mean (mL)24.0 ± 41.524.5 ± 43.322.4 ± 36.1.899
IPSS total17.2 ± 6.918.1 ± 7.214.2 ± 5.1.100
 Storage score7.7 ± 3.57.8 ± 3.67.5 ± 3.3.780
  Pollakisuria3.0 ± 1.63.1 ± 1.62.8 ± 1.8.602
  Urgency1.9 ± 1.82.0 ± 1.91.5 ± 1.4.469
  Nocturia2.8 ± 1.32.7 ± 1.33.1 ± 1.4.385
 Voiding score7.2 ± 4.37.9 ± 4.35.0 ± 3.5.051
  Intermittency2.2 ± 1.92.4 ± 2.01.7 ± 1.7.334
  Slow stream3.2 ± 1.83.6 ± 1.62.1 ± 1.9.013
  Straining1.7 ± 1.81.9 ± 1.91.2 ± 1.3.242
 Postmicturition score*2.3 ± 1.82.5 ± 1.91.7 ± 1.6.233
QOL score4.8 ± 1.04.9 ± 1.04.6 ± 1.1.442

Score: mean ± standard deviation (SD); postmicturition score*, domain for feeling of incomplete emptying.