Research Article

Microbiota, Prostatitis, and Fertility: Bacterial Diversity as a Possible Health Ally

Table 2

Seminal quality and oxidative stress in prostatitis-like symptoms men and fertile men.

Fertile group, control, median (range)Prostatitis-like symptoms, median (range) value

Seminal volume (mL)4 (1.5–4.5)3 (1.5–7.5)0.7460
Progressive motility (%)55.5 (41.5–81.0)57 (6.0–64.0)0.6667
Nonprogressive motility (%)6.5 (2.0–16.0)6.0 (1.0–25.0)0.9524
Immotile spermatozoa (%)39.0 (17.0–45.0)42.0 (29.0–90.0)0.8016
Concentration/mL (106/mL)80.0 (40.5–270.0)205.0 (7.0–254.0)0.9444
Total concentration (106/ejaculate)178.2 (115.5–1080.0)431.8 (22.4–1538.0)0.8016
Viability (%)79.0 (77.0–90.0)70.0 (49.0–85.0)0.1667
Sperm with normal morphology (%)4.8 (4.2–8.6)4.4 (2.8–6.8)0.8016
Teratozoospermia index1.4 (1.1–1.5)1.2 (1.1–1.5)0.2222
High mitochondrial membrane potential (%)63.2 (44.2–7.5)50.0 (12.3–55.5)0.0556
Plasma membrane integrity (%)64.8 (48.1–84.4)35.8 (6.2–69.7)0.1508
ROS production (%)64.3 (50.5–86.2)55.7 (17.7–61.9)0.0556
DNA fragmentation index (%)10.6 (10.4–11.4)11.1 (10.5–14.3)0.3889
Membrane lipid peroxidation (%)49.8 (9.1–80.5)67.0 (44.9–93.3)0.4127
Antioxidant capacity of seminal plasma %)61.0 (45.3–81.4)62.0 (9.5–69.3)0.5317
Serum nitric oxide (µM)3.7 (2.1–13.0)3.0 (1.7–4.1)0.5000
Plasma nitric oxide (µM)1.5 (0.6–1.7)0.5 (0.2–1.9)0.3016
PSA (ng/mL)0.0 (0.0–1.4)0.9 (0.0–120.0)0.3651

Mann–Whitney test. Data indicate median and range.