Research Article

Fast Track Surgery as the Latest Multimodal Strategy of Enhanced Recovery after Urethroplasty

Table 5

The FTS protocol for the supervision of patients with urethroplasty for urethral stricture.

FTS protocol for the urethroplasty:
Preoperative periodIntraoperative periodPostoperative period

Informing the patient about the disease, treatment options, and possible outcomes, indicating the average effectiveness, risks of complications, typical post-operative condition, timing of catheterization, hospitalization, possible methods of prerehabilitation, and further rehabilitation methodsPreferred method of anesthesia-local anesthesia/multimodal anesthesiaEarly fluids intake (2-3 hours after surgery) and food (6 hours after surgery)

One-day concept-the patient undergoes most of the preoperative examinations in one day, without the need for multiple repreparation. The order of examinations and tests is optimized and sorted to achieve the desired outcome

Rigorous evaluation of indications for surgical treatment: Qmax < 12 ml/s
Urethral lumen diameter <4 mm
Presence of residual urine
Presence of urethral distraction defect
Heating of the patient during the operation with the control of normothermiaEarly activation (6–8 hours after surgery, after evaluation by an anesthesiologist)

Assessment of the possibility of patient compliance with the protocol and its feasibility in the medical institutionHeating of infusion solutions and inhalation gasesPhysical therapy (breathing exercises, walking, and other exercises)

Preventive administration of antihistamines and antacids drugsMinimally invasive surgical approachesMultimodal prevention of nausea and vomiting (metoclopramide + ondansetron)

Refusal of preoperative sedationThe rejection of the use of monopolar coagulation and resectionRemoval of the urethral catheter after performing pericatheter urethrography no later than the seventh day after surgery

Prerehabilitation based on indications:
Age group
Obesity
Exhaustion
The sarcopenia
Impaired carbohydrate tolerance or diabetes mellitus
Application of bipolar coagulationUse of drugs that improve microcirculation, reparants, and hyperbaric oxygenation (in the mode of 1.0–1.5 ATM, for 45 minutes, 5–10 sessions; in the absence of contraindications)

Preoperative antibiotic therapy according to the testimony:
the presence of latent or obvious infection of the genitourinary system (according to the results of bacteriological research, real-time PCR, and infection of other organs
The rejection of coagulation on the spongy body of the urethraThe use of enzyme drugs (longidase, rectal suppositories) after 14 days after surgery in courses of 20 pieces with an interval of 2 days every 6 months

Multidisciplinary examination of patients:
Urologist
Anesthetist
ENT doctor
Dentist
General practitioner/Cardiologist
The radiologist physical therapy doctor
And other specialists as needed
Sealed continuous urethral suture with 4–6/0 monofilament threadContinuation of prevention of thromboembolic complications by compression of the lower extremities and the use of low-molecular-weight heparins

Performing CT/MRI of the small pelvis, CT/RI MRI of the urinary system, CT/RI MRI-urethrography with 3D-modeling, assessment of the state of the bone and joint apparatus of the pelvis, organsUse of platelet-rich plasma as injections into the submucosal layer of the urethra and surrounding tissuesMultimodal analgesia for pain control (Dexketoprofen + paracetomol)

A rich carbohydrate diet (if there are no contraindications) and 200 ml of liquid protein 2.5 hours before surgeryUse fibrin glue locally at the urethral seamUse of chewing gum on the first and second day after surgery

The last meal during the operation in the morning hours at 21-22 hours the day before, during the operation in the afternoon no later than 6 hours before the operationUse of silicone urethral catheters 14–16 chMonitoring of blood and urine parameters on the first day after surgery

Antibiotic prophylaxis 60 minutes before surgery with 3rd generation cephalosporinsThe rejection of the use of drainsStrict glycemic control in patients with impaired carbohydrate tolerance and diabetes mellitus

Shaving of the surgical field with subsequent treatment with solutions of skin antisepticsSealed cosmetic skin seam with no loose ends or knots on the skinA detailed discussion of the behavior of the patient and the rehabilitation plan before the discharge

Oral rinsing with an aqueous solution of chlorhexidine during planned urethroplasty using buccal mucosa graftThe adhesive bandage on the skinDetailed written instructions in the discharge documents

Prevention of thromboembolic complications by compression of the lower extremities and administration of low-molecular-weight heparinsIntraoperative euvolemiaStrict plan of follow-up examinations in the post-operative period

Avoiding the use of cleansing enemasStrict adherence to postoperative hygiene of the genitals (when using an adhesive bandage, the patient is recommended to take a hygienic shower daily from the second day)

Transfer of the patient to a slageless diet 2-3 days before surgeryDischarge from the hospital 1–3 days after the operation with the transfer of the patient to outpatient observation

Preparation of the intestines with laxatives or once microclystersRecommended return to work 2 days after removal of urethral catheter