Does Cytomegalovirus Develop Resistance following Antiviral Prophylaxis and Treatment in Renal Transplant Patients in Kuwait?

Table 2

UL54 mutations in clinical CMV isolates resistant to GCV [9].

Region	UL54 mutation	Amino acid change
IV	N408D; F412C; D413E	Asparagine to aspartic acid; Phenylalanine to cycteine; Aspartic acid to glutamic acid
δ-region C	L501F	Leucine to phenylalanine
	L501I	Leucine to isoleucine
	T503I	Threonine to isoleucine
	K503R	Lysine to arginine
	K513E	Lysine to glutamic acid
	P522A	Proline to alanine
	T700A	Threonine to alanine
II	T700A	Threonine to alanine
	M715V	Valine to methionine
	I722V	Isoleucine to valine
VI	V781I	Valine to isoleucine
III	L802M	Leucine to methionine
	A809V	Alanine to valine
	G841A	Glycine to alanine
Other	S676G	Serine to glycine
	G678S	Glycine to serine
	Y751H	Tyrosine to histidine