Retrovirus Entry by Endocytosis and Cathepsin Proteases

Table 3

Differential internalization pathways of HIV and MLV infections.

Viruses	Internalization pathway	Cell lines	Reference
Ecotropic MLV	Dynamin dependent	Mouse NIH3T3, human TE671, rat XC	[52]
	Dynamin-, clathrin independent	Human HeLa	[75]
Amphotropic MLV	Dynamin dependent	Mouse NIH3T3, human TE671, rat XC	[52]
	Caveolin dependent	Mouse NIH3T3	[74]
Polytropic MLV	Dynamin dependent	Mouse NIH3T3, human TE671, rat XC	[52]
Xenotropic MLV	Dynamin dependent	Mouse NIH3T3, human TE671, rat XC	[52]
CD4-dependent HIV	Dynamin dependent	Human HeLa	[95]
	Clathrin dependent	Human primary T lymphocyte	[95–97]
	Dynamin-, Eps15 dependent	Human HeLa	[98]
	Dynamin-, Eps15 independent	Human 293T, HeLa, TE671	[21]
CD4-independent HIV	Dynamin-, Eps15 dependent	Human 293T, HeLa, TE671	[21]