Research Article
Therapeutic Promises of Plant Metabolites against Monkeypox Virus: An In Silico Study
Table 4
List of drug targets for curcumin, coumadin, piperine, and gedunin.
| | Metabolites | Drug targets | Common name | Target class | Probability |
| | Curcumin | MAO (monoamine oxidase A) | MAO-A | Oxidoreductase | | | Beta amyloid A4 precursor protein | APP | Membrane receptor | | | Histone acetyltransferase p300 | EP300 | Writer | | | Prostaglandin E synthase | PTGES | Enzyme | |
| | Coumadin | MAP kinase ERK2 | MAPK1 | Kinase | | | Aldose reductase | AKR1B1 | Enzyme | |
| | Piperine | Monoamine oxidase B | MAOB | Oxidoreductase | | | Sigma opioid receptor | SIGMAR1 | Membrane receptor | |
| | Gedunin | Macrophage migration inhibitory factor | MIF | Enzyme | | | Kappa opioid receptor | OPRK1 | Family A G protein-coupled receptor | | | Delta opioid receptor | OPRD1 | Family A G protein-coupled receptor | |
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