Coordination Reactions and Noncovalent Interactions of Polyamines with Nucleotides in Binary Systems and with Nucleotides and Copper(II) Ion in Ternary Systems
Table 1
Overall protonation constants, overall stability constants , and equilibrium constants of adducts formation in AMP/tn-1, AMP/tn-2, CMP/tn-1, and CMP)/tn-2 systems.
Systems
Equilibrium
log
Ligands
AMP + H+ H(AMP)
6.43
6.43
AMP + 2H+ H2(AMP)
10.45
4.02
CMP + H+ H(CMP)
6.42
6.42
CMP + 2H+ H2(CMP)
10.90
4.48
tn-1 + H+ H(tn-1)
9.96 (1)
9.96
tn-1 + 2H+ H2(tn-1)
16.62 (1)
6.66
tn-2 + H+ H(tn-2)
9.80 (1)
9.80
tn-2 + 2H+ H2(tn-2)
16.41 (1)
6.61
AMP/tn-1
AMP + 4H+ + tn-1 (AMP)H4(tn-1)
31.55 (6)
4.49
AMP + 3H+ + tn-1 (AMP)H3(tn-1)
27.63 (6)
4.58
AMP + 2H+ + tn-1 (AMP)H2(tn-1)
21.13 (6)
4.51
AMP + H+ + tn-1 (AMP)H(tn-1)
13.08 (6)
3.12
CMP/tn-1
CMP + 4H+ + tn-1 (CMP)H4(tn-1)
30.87 (5)
3.91
CMP + 3H+ + tn-1 (CMP)H3(tn-1)
26.50 (4)
4.02
CMP + 2H+ + tn-1 (CMP)H2(tn-1)
20.20 (4)
4.14
CMP + H+ + tn-1 (CMP)H(tn-1)
12.50 (3)
2.91
AMP/tn-2
AMP + 4H+ + tn-2 (AMP)H4(tn-2)
30.81 (5)
3.95
AMP + 3H+ + tn-2 (AMP)H3(tn-2)
26.76 (4)
3.92
AMP + 2H+ + tn-2 (AMP)H2(tn-2)
20.40 (4)
3.99
AMP + H+ + tn-2 (AMP)H(tn-2)
12.91 (3)
3.11
CMP/tn-2
CMP + 4H+ + tn-2 (CMP)H4(tn-2)
30.77 (1)
3.46
CMP + 3H+ + tn-2 (CMP)H3(tn-2)
26.38 (1)
3.55
CMP + 2H+ + tn-2 (CMP)H2(tn-2)
20.19 (1)
3.78
CMP + H+ + tn-2 (CMP)H(tn-2)
12.88 (1)
3.08
*log were calculated using protonation and overall stability constants of particular species, for example: log log log .
