Bioinorganic Chemistry and Applications

Research Article

Coordination Reactions and Noncovalent Interactions of Polyamines with Nucleotides in Binary Systems and with Nucleotides and Copper(II) Ion in Ternary Systems

Table 3

Overall stability constants (log ) and equilibrium constants (log ) of complexes formation in Cu(II)/tn- , Cu(II)/tn- , Cu(II)/ , Cu(II)/ , Cu(II)/AMP/tn-1, Cu(II)/AMP/tn-1, Cu(II)/CMP/tn-1, and Cu(II)/CMP/tn-2 systems.
SystemsEquilibriumlog log
Cu(II)/tn-1Cu + H+ + tn-1 CuH(tn-1) 15.48 (10) 5.52
Cu + tn-1 Cu(tn-1)10.75 (7)10.75
Cu + 2(tn-1) Cu(tn-1)219.60 (6) 8.85
Cu(II)/tn-2Cu + H+ + tn-2 CuH(tn-2)14.51 (10) 4.71
Cu + tn-2 Cu(tn-2)10.32 (2)10.32
Cu + 2(tn-2) Cu(tn-2)219.45 (3) 9.13
Cu + 3(tn-2) Cu(tn-2)325.11 (5) 5.66
Cu + 3(tn-2) + H2O Cu(tn-2)3(OH) + H+14.67 (6)—
Cu(II)/AMPCu + AMP Cu(AMP) 3.02 (8)3.02
Cu + AMP + H2O Cu(AMP)(OH) + H+ (5)—
Cu(II)/CMPCu + CMP Cu(CMP) 2.71 (6)2.71
Cu + CMP + H2O Cu(CMP)(OH) + H+ (8)—
Cu(II)/AMP/tn-1Cu + 3H+ + AMP + tn-1 Cu(AMP)H3(tn-1)30.73 (3)—
Cu + 2H+ + AMP + tn-1 Cu(AMP)H2(tn-1)26.03 (4) 6.39
Cu + AMP + tn-1 Cu(AMP)(tn-1)14.86 (7)11.84
Cu(II)/CMP/tn-1Cu + 3H+ + CMP + tn-1 Cu(CMP)H3(tn-1)30.81 (1)—
Cu + 2H+ + CMP + tn-1 Cu(CMP)H2(tn-1)25.30 (6) 5.97
Cu + CMP + tn-1 Cu(CMP)(tn-1)14.16 (2)11.14
Cu(II)/AMP/tn-2Cu + 3H+ + AMP + tn-2 Cu(AMP)H3(tn-2)29.63 (8)—
Cu(II)/CMP/tn-2Cu + 2H+ + CMP + tn-2 Cu(CMP)H2(tn-2)25.10 (4) 5.98
were calculated using protonation and overall stability constants of particular species, for example: log  .