DNA Binding and Antitumor Activity of α-Diimineplatinum(II) and Palladium(II) Dithiocarbamate Complexes

<table>Fluorescence emission spectra of interacted EB-DNA in the absence (1) and presence of different concentrations of [Pt(bpy)(Oct-dtc)]NO<sub>3</sub> and the inset for [Pd(bpy)(Oct-dtc)]NO<sub>3</sub>: 33  <i>μ</i>M (2), 71 <i>μΜ</i> (3), and 111 <i>μ</i>M (4) and 12 <i>μ</i>M (2), 35 <i>μ</i>M (3), and 55 <i>μ</i>M (4), respectively, at 300 K.</table>

Bioinorganic Chemistry and Applications

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Figure 10

Figure 10: DNA Binding and Antitumor Activity of α-Diimineplatinum(II) and Palladium(II) Dithiocarbamate Complexes 