DNA Interaction and DNA Cleavage Studies of a New Platinum(II) Complex Containing Aliphatic and Aromatic Dinitrogen Ligands
Figure 8
Cleavage of SC pUC19 DNA (50 μM) by platinum complex (100 μM) in the presence of H2O2 (100 μM), in 10 mM Tris-HCl/1 mM EDTA buffer (pH 8.0). lane 1: DNA Marker; lane 2: DNA control; lane 3: DNA + complex; lane 4: DNA + complex 1 + H2O2; lane 5: DNA + complex + H2O2 + DMSO (4 μL); lane 6: DNA + complex 1 + H2O2 + NaN3 (100 μM).
