Identification of Binding Mode of a Platinum (II) Complex, <svg style="vertical-align:-4.50008pt;width:48.487499px;" id="M1" height="21.0375" version="1.1" viewBox="0 0 48.487499 21.0375" width="48.487499"  xmlns="http://www.w3.org/2000/svg">
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			<text transform="matrix(1,0,0,-1,-71.95,59.7)">
				<tspan style="font-size: 17.93px; " x="0" y="0">P</tspan>
				<tspan style="font-size: 17.93px; " x="9.9886808" y="0">t</tspan>
				<tspan style="font-size: 17.93px; " x="14.974055" y="0">C</tspan>
				<tspan style="font-size: 17.93px; " x="26.935366" y="0">l</tspan>
			</text>

			<text transform="matrix(1,0,0,-1,-40.03,55.22)">
				<tspan style="font-size: 12.55px; " x="0" y="0">𝟐</tspan>
			</text>

		</g>
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</svg>(DIP), and Calf Thymus DNA

<table>Effect of DNA on the fluorescence spectra of Pt complex (<svg height="15.9" id="M47" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 75.650002 15.9" width="75.650002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,15.638)"><path d="M249 635q70 0 116 -43t46 -105q0 -46 -28 -80q-22 -25 -80 -64q62 -35 97 -75t35 -99q0 -81 -63 -131t-135 -50q-83 0 -137.5 45.5t-54.5 123.5q0 52 45 95q29 28 89 64q-109 62 -109 155q0 66 50.5 115t128.5 49zM238 603q-42 0 -67.5 -31t-25.5 -72q0 -50 32.5 -79.5
t98.5 -62.5q61 48 61 124q0 59 -29.5 90t-69.5 31zM248 20q46 0 76.5 33.5t30.5 89.5q0 50 -39 85.5t-110 71.5q-81 -54 -81 -137q0 -67 35.5 -105t87.5 -38z" id="x38"></path></g><g transform="matrix(.017,-0,0,-.017,8.222,15.638)"><path d="M113 -12q-24 0 -39.5 16t-15.5 42q0 24 16 40.5t40 16.5t40 -16.5t16 -40.5q0 -26 -16 -42t-41 -16z" id="x2E"></path></g><g transform="matrix(.017,-0,0,-.017,12.098,15.638)"><path d="M285 378v-2q65 -13 102 -54.5t37 -97.5q0 -57 -30.5 -104.5t-74 -75t-85.5 -42t-72 -14.5q-31 0 -59.5 11t-40.5 23q-19 18 -16 36q1 16 23 33q13 10 24 0q58 -51 124 -51q55 0 88 40t33 112q0 64 -39 96.5t-88 32.5q-29 0 -64 -11l-6 29q77 25 118 57.5t41 84.5
q0 45 -26.5 69.5t-68.5 24.5q-67 0 -120 -79l-20 20l43 63q51 56 127 56h1q66 0 107 -37t41 -95q0 -42 -31 -71q-22 -23 -68 -54z" id="x33"></path></g><g transform="matrix(.017,-0,0,-.017,20.257,15.638)"><path d="M456 178h-96v-72q0 -51 12.5 -62.5t72.5 -16.5v-27h-256v27q65 5 78 17t13 62v72h-260v28q182 271 300 426h40v-407h96v-47zM280 225v295h-2q-107 -148 -196 -295h198z" id="x34"></path></g><g transform="matrix(.017,-0,0,-.017,32.19,15.638)"><path d="M528 54l-36 -38l-198 201l-198 -201l-36 38l197 200l-197 201l36 38l198 -202l198 202l36 -38l-197 -201z" id="xD7"></path></g><g transform="matrix(.017,-0,0,-.017,45.942,15.638)"><path d="M384 0h-275v27q67 5 81.5 18.5t14.5 68.5v385q0 38 -7.5 47.5t-40.5 10.5l-48 2v24q85 15 178 52v-521q0 -55 14.5 -68.5t82.5 -18.5v-27z" id="x31"></path></g><g transform="matrix(.017,-0,0,-.017,54.102,15.638)"><path d="M241 635q53 0 94 -28.5t63.5 -76t33.5 -102.5t11 -116q0 -58 -11 -112.5t-34 -103.5t-63.5 -78.5t-94.5 -29.5t-95 28t-64.5 75t-34.5 102.5t-11 118.5q0 58 11.5 112.5t34.5 103t64.5 78t95.5 29.5zM238 602q-32 0 -55.5 -25t-35.5 -68t-17.5 -91t-5.5 -105
q0 -76 10 -138.5t37 -107.5t69 -45q32 0 55.5 25t35.5 68.5t17.5 91.5t5.5 105t-5.5 105.5t-18 92t-36 68t-56.5 24.5z" id="x30"></path></g>
<g transform="matrix(.012,-0,0,-.012,62.262,7.475)"><path d="M535 230h-483v50h483v-50z" id="x2212"></path></g><g transform="matrix(.012,-0,0,-.012,69.247,7.475)"><path d="M153 550l-26 -186q79 31 111 31q90 0 141.5 -51t51.5 -119q0 -93 -89 -166q-85 -69 -173 -71q-32 0 -61.5 11.5t-41.5 23.5q-18 17 -17 34q2 16 22 33q14 9 26 -1q61 -50 124 -50q60 0 93 43.5t33 104.5q0 69 -41.5 110t-121.5 41q-53 0 -102 -20l38 305h286l6 -8
l-26 -65h-233z" id="x35"></path></g>
</svg> M) in Tris-HCl (10 mM) buffer. <svg height="11.9625" id="M48" style="vertical-align:-3.3907pt" version="1.1" viewbox="0 0 11.175 11.9625" width="11.175" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,7.675)"><path d="M393 379q-9 -16 -28 -29q-15 -10 -23 -2q-19 19 -36 19q-21 0 -52 -38q-57 -72 -82 -126l-40 -197q-23 -3 -75 -18l-7 7q49 196 74 335q7 43 -2 43q-7 0 -30 -14.5t-47 -37.5l-16 23q37 42 82 73t67 31q41 0 15 -113l-11 -50h4q41 71 85 117t77 46q29 0 45 -26
q13 -21 0 -43z" id="x1D45F"></path></g>
<g transform="matrix(.012,-0,0,-.012,7.238,11.762)"><path d="M244 607q0 -25 -15.5 -43t-37.5 -18q-19 0 -32 13t-13 35q0 21 15 41t39 20q20 0 32 -14t12 -34zM222 91q-29 -33 -79 -68t-75 -35q-13 0 -19 7.5t-6 31t10 65.5l62 253q5 26 -1 26q-21 0 -72 -43l-13 24q43 40 91 68t71 28q30 0 10 -78l-71 -274q-8 -30 3 -30
q16 0 76 48z" id="x1D456"></path></g>
</svg> = [DNA]/[Complex] = 0.0, 0.2, 0.6, 0.8, 1, 1.2.</table>

Bioinorganic Chemistry and Applications

fig6

Figure 6

Figure 6: Identification of Binding Mode of a Platinum (II) Complex, <svg style="vertical-align:-4.50008pt;width:48.487499px;" id="M1" height="21.0375" version="1.1" viewBox="0 0 48.487499 21.0375" width="48.487499"  xmlns="http://www.w3.org/2000/svg">
	<g transform="matrix(1.25,0,0,-1.25,0,21.0375)">
		<g transform="translate(72,-55.17)">
			<text transform="matrix(1,0,0,-1,-71.95,59.7)">
				<tspan style="font-size: 17.93px; " x="0" y="0">P</tspan>
				<tspan style="font-size: 17.93px; " x="9.9886808" y="0">t</tspan>
				<tspan style="font-size: 17.93px; " x="14.974055" y="0">C</tspan>
				<tspan style="font-size: 17.93px; " x="26.935366" y="0">l</tspan>
			</text>

			<text transform="matrix(1,0,0,-1,-40.03,55.22)">
				<tspan style="font-size: 12.55px; " x="0" y="0">𝟐</tspan>
			</text>

		</g>
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</svg>(DIP), and Calf Thymus DNA 

Figure 6 | Identification of Binding Mode of a Platinum (II) Complex, 
	
		
			
				P
				t
				C
				l
			

			
				𝟐
			

		
	
(DIP), and Calf Thymus DNA 

Bioinorganic Chemistry and Applications

Identification of Binding Mode of a Platinum (II) Complex, P t C l 𝟐 (DIP), and Calf Thymus DNA

Figure 6

Identification of Binding Mode of a Platinum (II) Complex, (DIP), and Calf Thymus DNA