Research Article

Synthesis, Characterization, and Bioactivity of Schiff Bases and Their , , , and Complexes Derived from Chloroacetophenone Isomers with S-Benzyldithiocarbazate and the X-Ray Crystal Structure of S-Benzyl-β-N-(4-chlorophenyl)methylenedithiocarbazate

Table 7

(a) Qualitative antimicrobial assay mean results* (diameter of inhibition zones in mm). (b) Qualitative antimicrobial assay mean results* (diameter of inhibition zones in mm).
(a)

CompoundGram-positive bacteriaGram-negative bacteriaFungus
S. aureus B. cereus K. rhizophila E. coli P. aeruginosa C. freundii Aspergillus niger

NS217.6021.6319.0115.6213.8819.60
Zn(NS2)216.2318.1218.348.6013.6316.9923.15
Cd(NS2)28.908.1625.767.4315.278.3329.98
Ni(NS2)27.408.5113.538.8817.17
Cu(NS2)27.097.45
NS46.5311.50
Zn(NS4)29.198.177.409.69
Cd(NS4)27.776.6130.056.81
Ni(NS4)210.8710.229.1312.99
Cu(NS4)210.336.648.219.99

(b)

Controls and reference compoundsGram-positive bacteriaGram-negative bacteriaFungus
S. aureus B. cereus K. rhizophila E. coli P. aeruginosa C. freundii Aspergillus niger

DMSO
Streptomycin14.0815.6712.2014.4413.54Not available
Neomycin18.1418.5218.5716.5821.8718.91
Chloramphenicol25.8621.7025.8715.0119.80
SBDTC19.0722.7313.3315.7014.9021.1918.57
Amphotericin B19.17

Zones of inhibition of diameters 14 mm and above were considered to be significant, 9 mm–14 mm were considered moderate, and less than 9 mm were considered weak and insignificant. (—) refers to absence of measurable inhibitory action.