Research Article

Synthesis, Characterization, and Bioactivity of Schiff Bases and Their , , , and Complexes Derived from Chloroacetophenone Isomers with S-Benzyldithiocarbazate and the X-Ray Crystal Structure of S-Benzyl-β-N-(4-chlorophenyl)methylenedithiocarbazate

Table 9

Shows the minimum inhibitory concentration (MIC) of the compounds.

CompoundMIC (mg/mL)
S. aureus B. cereus K. rhizophila E. coli P. aeruginosa C. freundii

NS2<6.25<6.2525<6.2550<6.25
Zn(NS2)2<6.25<6.2512.50<6.25<6.25<6.25
Cd(NS2)2<6.25100<6.25
Ni(NS2)2100100
Cu(NS2)2
NS412.50
Zn(NS4)250
Cd(NS4)2<6.25
Ni(NS4)22550
Cu(NS4)2<6.25<6.25
SBDTC<6.25<6.25<6.25<6.250.78*<6.25
Streptomycin0.001563*0.000391*>0.10*0.0008*0.004*0.004*
NeomycinN/A1.10*0.0039*0.0064*N/A0.032*
Chloramphenicol0.005*0.01*0.05*0.004*0.02*0.002*

— refers to the absence of an MIC value for a certain compound as it was not investigated for its MIC due to its low activity. *refers to an MIC value that was obtained from the previous literature or experiments. N/A: (not available).