Research Article
Synthesis, Characterization, and Antibacterial Studies of Pd(II) and Pt(II) Complexes of Some Diaminopyrimidine Derivatives
Table 4
MBC values (mg/mL) of the metal complexes on selected bacteria.
| | Complexes | E. coli | P. aeruginosa | S. aureus | S. faecalis | B. cereus | B. pumilus | K. pneumonia | P. vulgaris |
| | Pd(tmp)2Cl2 | >20.0 | NI | 20.0 | NI | 5.0 | NI | 10.0 | 20.0 | | Pd(tmp)2(NCS)2 | 10.0 | NI | NI | >20.0 | NI | NI | NI | NI | | Pt(tmp)2Cl2 | 20.0 | NI | >20.0 | NI | 10.0 | NI | 10.0 | >20.0 | | Pt(tmp)2(NCS)2 | >20.0 | NI | 10.0 | NI | >20.0 | NI | NI | 20.0 | | Pd(pyrm)2Cl2 | NI | 10.0 | 2.5 | NI | NI | 2.5 | 0.31 | NI | | Pd(pyrm)2(NCS)2 | NI | 10.0 | 0.63 | NI | NI | 1.25 | 2.50 | NI | | Pt(pyrm)2Cl2 | 20.0 | NI | 10.0 | 10.0 | NI | NI | NI | NI | | Pt(pyrm)2(NCS)2 | >20.0 | NI | 20.0 | NI | 10.0 | NI | NI | 20.0 | | Pyrimethamine | >20.0 | NA | >20.0 | >20.0 | >20.0 | NA | 20.0 | >20.0 | | Trimethoprim | >20.0 | NA | 20.0 | >20.0 | 20.0 | NA | 20.0 | 20.0 |
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