Potentiometric and Blood Plasma Simulation Studies of Nickel(II) Complexes of Poly(amino)amido Pentadentate Ligands: Computer Aided Metal-Based Drug Design

Figure 2

Experimental and theoretical (solid line) (a) formation function and (b) deprotonation function curves for Ni(II)-L1 system at 25°C and an ionic strength 0.15 M (Cl⁻¹). M : L ratios 1 : 1 (□), 1 : 2 (◊), and 1 : 3 () are displayed. The theoretical line was calculated using model 1 given in Table 1.

(a)

(b)