Synthesis and Characterization with Antineoplastic, Biochemical, Cytotoxic, and Antimicrobial Studies of Schiff Base Cu(II) Ion Complexes

Table 11

Histopathological effect of test compounds.

Name of the experiment	Observation
	Size	Number of lymphocytes	Necrotic area	Inflammatory area
EAC	↑↑↑	↓↓↓
A	↓↓↓	↑↑↑	↑↑↑	↑↑↑
B	↓	↑	↑	↑
C	↓↓	↑↑	↑↑	↑↑
Bleomycin	↓↓↓	↑↑↑	↑↑↑	↑↑↑

A = K[Cu(SB-1)(SCN)], B = [Cu(SB-2)NN], NN = 2-aminopyridine, and C = [Cu(SB-2)(NN)], NN = 2-phenylenediamine.
↑ = increase, ↑↑ = moderately increase, and ↑↑↑ = greatly increase.
↓ = decrease, ↓↓ = moderately decrease, and ↓↓↓ = greatly decrease.