Synthesis and Characterization with Antineoplastic, Biochemical, Cytotoxic, and Antimicrobial Studies of Schiff Base Cu(II) Ion Complexes

Table 5

The effect of test compounds on survival time of EAC cell bearing mice.

Name of experiment	Drugs	Dose	Mean survival time	% of increase life span
Control (EAC bearing mice)			(21.37 ± 1.7)
EAC + bleomycin		0.3 mg/kg	40 ± 1.2	87.17
A	Synthetic	8 mg/kg	29 ± 2.6	35.70
B	Synthetic	10 mg/kg	25 ± 1.4	16.98
C	Synthetic	16 mg/kg	26.14 ± 1.1	22.32

A = K[Cu(SB-1)(SCN)], B = [Cu(SB-2)NN], NN = 2-aminopyridine, and C = [Cu(SB-2)(NN)], NN = 2-phenylenediamine.